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What are Transfer Factors? How they change your health

 Transfer Factors are small molecules that intelligently regulate immune system activities such as recognition, response and memory of foreign invaders. Transfer factors increase, decrease, and educates helper T Cells, Natural Killer (NK) cells, and Immunoglobulin Antibodies (IgA) according to your needs. They are found in the bodies of all higher animals. They are transferred from a mother who breast feeds to her new born infant to support the infant's immune system.

Dr. H. Sherwood Lawrence discovered he could transfer the successful immune response of a person who was exposed to a foreign invader by transferring the donor's dialyzable leukocytes to a naive recipient in the 1940s. He called this process the "transfer factor". Since then, researchers conducted thousands of transfer factor studies with mixed results depending on dosage, experimental design, and other factors. After 1992, Kirkpatrick distinguished specific transfer factors at the molecular level. His results indicate that transfer factors are constituted by a large group of amino acid molecules, of low molecular weights, from 1.0 to 6.0 kDa. Medline, the National Institute of Health’s online service published over 1,200 scientific abstracts on the immune benefits of transfer factors. An estimated $40,000,000 was spent on research. (See references)

During the early 1990s, David Lisonbee founder and president of 4Life Research discovered how pure transfer factor molecules can be extracted from colostrum and egg yolks and received patents for the processes. 4Life Research chose colostrum and egg yolks because they knew that cows and chickens are exposed to a broad spectrum of foreign invaders from being outdoors and eating off the ground. Cows and chickens also make transfer factors that are identical to transfer factors that healthy human immune systems develop if they are exposed to these potentially dangerous foreign invaders.

Currently, 4Life produces standardized health nutrition supplements that transfer this experienced immune system information to naive recipients so their immune systems are prepared to deal with these microscopic threats. Independent study results show that 4Life's transfer factors increase natural killer cell activities by 283 percent in pure form and 437 percent in their proprietary blend Transfer Factor Plus Tri-Factor Formula. This is more effective than any other method known at this time. (See chart) Transfer factors also increase immunoglobulin antibodies (IgA) by 73 percent.

The FDA generally regards transfer factors as safe. Pure transfer factors do not demonstrate toxicity even at 200 times the recommended dose. Transfer factors are a normal part of our bodies' so there are no drug interactions with pure transfer factors.

Independent comparison studies show other forms of extraction and immune system support products are relatively costly and ineffective. Most just boost immune system activity which can leave your immune system out of balance. As with many revolutionary breakthroughs that threaten convention, 4Life transfer factors are being met with sometimes criminal contempt (1).

While 4life transfer factor molecules speed up recognition of threats, modulate your immune system response, and remembers these invaders so your immune system is prepared if the threat returns, there is something more. Through thousands of studies and years of research, 4Life researchers found even smaller molecules. They call these nanofractions nanofactors. Nanofactors give your immune system the intuition to know when to act, how to act, and when to rest after it has the threat under control. Taking 4Life Transfer Factors with nanofractions effectively helps your immune system recognize and fight off threats or foreign invaders, and then preserves energy by reducing your immune system response when the threat is under control according to your individual needs. This restores your energy levels so you can do more of the things you want to do.

Another reason for using transfer factors comes from the increase in new antibiotic resistant bacteria, and the many adverse side effects of antibiotics. According to recent methodological studies from Russia, the natural immune system support provided by transfer factors offers so many benefits over antibiotics that they now recommend that their doctors use transfer factors before resorting to the use of antibiotics.

The daily need for 4Life Transfer Factors in children and adults comes from the interplay of genetic and environmental threats that weaken and/or over-activate healthy immune systems responses to foreign invaders. It is well known that pollution, poor eating habits, lack of exercise, and legal and illegal drugs, threaten our health and lifestyles. Transfer factor is one of those health nutrition supplements that can change the course of your life for the better.

1. Viza, D. (1996). AIDS and transfer factor: myths, certainties and realities. Biotherapy (Dordrecht, Netherlands), 9(1-3), 17-26. Persistent link to this record



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Industry Authority Sites



• Natural Products Association

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Colostrum TF vs Vaccine vs 4Life Transfer Factor



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4 Life™ News Brief:

Independent Bio-Assay Overview

December 11, 1998

Salt Lake City, UT - 4Life Research, a Provo, Utah research and development company released its latest assaying

and testing for its new 4Life Transfer Factor™ product.

Transfer factor is a scientifically recognized delivery system for transferring immune system advantages from one

species to another. In the patented process licensed to 4Life, immune factors are generated in cows and then

"transferred" as a nutritional supplement to humans. Products manufactured incorporating the process are

anticipated by industry experts to be the "next wave" of nutritional supplementation, operating in the newly defined

area of "structure/function" claims. Dr. William Hennen, who is one of the world authorities on transfer factor, says

of the science and technology: "Transfer factor is a material that has the ability to modulate the immune system.

4Life Transfer Factor™ contains both materials that help the immune system respond more effectively and materials

to make sure the immune system is not over-responding."

4Life's founder and president, David Lisonbee said, "4Life has an agreement with the patent inventors to market

transfer factor. United States Patent No. 4,816,563, issued on March 28, 1989, is licensed to 4Life. This patent

describes the proprietary process used by 4Life to create its unique Transfer Factor™.

The only patent 4Life is aware of which identifies transfer factor in colostrum, the process for obtaining transfer

factor from colostrum and whey, and the patented method "to further concentrate and/or purify transfer factor" from

colostrum, is the one licensed to 4Life. It is United States Patent No. 4,816,563.

Laboratory Testing of 4Life's Transfer Factor™

According to William Hennen, Ph.D., Vice President of Research and Development at 4Life, "Each and every batch

of Transfer Factor™ is tested by an independent laboratory with established, documented credentials in assessing

for transfer factor activity. Very few laboratories have the experience or credentials to assay for TF activity. We go

to great lengths to assure the quality of transfer factor in our product. This is the reason our distributors are

consistently having such great success with Transfer Factor™. From infants to the elderly, reports keep coming in

every day with results that have matched or exceeded our every expectation. Transfer factor has nearly 50 years of

research and over 3,000 clinical studies and scientific papers proving its existence and effectiveness. Our licensed

patent proved for the first time that transfer factor exists in colostrum and that it can be successfully extracted and

assayed."

Independent Laboratories Show Transfer Factor Activity in 4Life's Transfer Factor™

Independent laboratory tests clearly indicate that 4Life's Transfer Factor™ shows significant transfer factor activity equal to

the effectiveness of the standard vaccine.

The biological and chemical testing laboratory, BioLogics Inc. states the following regarding 4Life's Transfer Factor™:

"BioLogics Inc. has completed testing the preparations of bovine colostrum you sent for evaluation for TF (transfer factor)

activity. Each preparation was evaluated for TF activity using a mouse foot- pad assay which measures delayed-type

hypersensitivity (DTH). The results are shown below. A preparation was considered active if it induced significant DTH

(p<0.005 or better) as compared to the response to [an] antigen in control mice which were naive (not treated with TF)."

Preparation tested Transfer Factor Transfer Factor

Presence Active

Vaccinated Controls 0.01>P>0.001 YES (P<0.01) Very Active

Mice injected with standard

antigen vaccine

Colostrum Fraction 0.20>P>0.10 NO (P>0.10) Failed

Normally fractionated colostrum

4Life Transfer Factor™ 0.01>P>0.001 YES (P<0.01) Very Active

Patented extract of colostrum

"Further, it is critical to understand that a proper transfer factor assay includes both a zero-point standard and a high-end

standard (to set the span of the scale.) The zero-point standard accounts for the nutritional value of the transfer factor

preparation and is represented by the fractionated colostrum listed in the second row above. A vaccinated control is the

GOLD STANDARD for establishing the high-end of the immunological scale as represented in the first row.

As was clearly shown, 4Life's Transfer Factor™ was not only measurably more potent than the normal colostrum of the

second row, it was equal to the vaccine standard in causing a strong immune response," stated Dr. Hennen.

Top Transfer Factor Researcher Tests 4Life's Transfer Factor™

One of the world's leading TF researchers has also tested 4Life's Transfer Factor™ using a mouse foot-pad assay.

"Three different colostrum extracts were tested, one of which was 4Life's Transfer Factor™. 4Life's Transfer Factor™ tested

highest in TF activity of any of the samples tested."

Molecular Weight Laboratory Testing of 4Life's Transfer Factor™

An independent laboratory experienced in molecular weight analysis tested samples of 4Life's Transfer Factor™ and found it

to contain exactly what 4Life claims it contains: Molecules in the molecular weight of 10,000 daltons or less. Bay

Bioanalytical Laboratory, Inc. stated in their report:

"[We] have reviewed the analysis of [4Life's] Transfer Factor performed in our laboratory using HPLC and a size exclusion

column coupled with a light scattering, refractive index and a UV detector. Based on our analysis we can conclude [that] the

analyzed fraction is composed primarily of molecules below 10,000 [daltons] molecular weight."

Bay Bioanalytical Laboratory, Inc.






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